
个人基本情况:
冯若飞,男,博士,教授,博士生导师。现任西北民族大学生物医学研究中心副主任,分管中心科学研究管理、学位点建设、研究生教育教学、国际交流与合作等工作。兼任中国细胞生物学学会资深会员、甘肃省免疫学会理事、甘肃省生物工程学会理事、甘肃省动物卫生标准化技术委员会委员、甘肃省临夏县动物疫病防控专家。2018年入选国家民委中青年英才计划,2020年获得甘肃省青年教师成才奖,2021年获得甘肃省优秀硕士学位论文指导教师称号。先后主持国家自然科学基金项目2项,主持其他各级各类项目18项,参与国家重大专项、863项目等科研项目等20余项。以第一作者或通讯作者发表学术论文80多篇,授权发明专利4件。
教育经历:
2011年09月-2014年06月 中国农业科学院研究生院预防兽医学 博士
2004年09月-2007年06月 西北民族大学 临床兽医学 硕士
1998年09月-2002年07月 西北民族学院 动物医学 学士
工作经历:
2002年07月至今在西北民族大学从事教学科研工作。
科研奖励:
2010年获得兰州市科技进步一等奖
2012年获得兰州市科技进步一等奖
2012年获得甘肃省科技进步二等奖
2013年获得兰州市科技进步三等奖
2018年获得华夏医学科技奖二等奖
2019年获得国家民委教学成果二等奖
2020年获得甘肃省科技进步二等奖
研究生培养情况:
已联合培养博士研究生1人,培养硕士研究生7人,联合培养在读博士2人,培养在读硕士7人,所培养硕士研究生获得国家奖学金2人,获得省优秀三好学生1人,获得省级优秀硕士论文1人,先后获得学校求知杯论文大赛一等奖2人,二等奖2人。
主要学术成果:
(1)Ruofei Feng(通讯作者).Encephalomyocarditis Virus Structural Protein VP3 Interacts with MAVS and Promotes its Autophagic Degradation to Interfere with the Type I Interferon Signaling Pathway. Front Biosci (Landmark Ed). 2024 Jul 25;29(7):273. doi: 10.31083/j.fbl2907273.
(2)Ruofei Feng(通讯作者).The complex interplay between encephalomyocarditis virus and the host defence system. Virulence. 2024 Dec;15(1):2383559. doi: 10.1080/21505594.2024.2383559.
(3)Ruofei Feng(通讯作者).Pseudorabies virus VHS protein abrogates interferon responses by blocking NF-κB and IRF3 nuclear translocation. Virol Sin. 2024 May 30:S1995-820X(24)00078-6. doi: 10.1016/j.virs.2024.05.009.
(4) Ruofei Feng(通讯作者). Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS. mSphere. 2024 Jun 25;9(6):e0023624. doi: 10.1128/msphere.00236-24. Epub 2024 May 17.
(5)Ruofei Feng(通讯作者).Pseudorabies virus UL38 attenuates the cGAS-STING signaling pathway by recruiting Tollip to promote STING for autophagy degradation. Virol J. 2024 May 8;21(1):107. doi: 10.1186/s12985-024-02379-x.
(6)Ruofei Feng(通讯作者).Mammalian reovirus µ1 protein attenuates RIG-I and MDA5-mediated signaling transduction by blocking IRF3 phosphorylation and nuclear translocation. Mol Immunol. 2024 Jun;170:131-143. doi: 10.1016/j.molimm.2024.04.010.
(7)Ruofei Feng(通讯作者).New perspective of small-molecule antiviral drugs development for RNA viruses. Virology. 2024 Jun;594:110042. doi: 10.1016/j.virol.2024.110042.
(8)Ruofei Feng(通讯作者).Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway. Viruses. 2024 Jan 24;16(2):174. doi: 10.3390/v16020174.
(9)Ruofei Feng(通讯作者). Construction, expression and assemble of EMCV VLPs and their potency evaluation. Virology. 2023 Jul;584:1-8. doi: 10.1016/j.virol.2023.04.011.
(10)Ruofei Feng(通讯作者). IFITM2 Presents Antiviral Response through Enhancing Type I IFN Signaling Pathway. Viruses. 2023 Mar 28;15(4):866. doi: 10.3390/v15040866.
(11)Ruofei Feng(通讯作者). HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection. Viruses. 2022 Aug 23;14(9):1851. doi: 10.3390/v14091851.
(12)Ruofei Feng(通讯作者). DDX56 inhibits PRV replication through regulation of IFN-β signaling pathway by targeting cGAS. Front Microbiol. 2022 Aug 10;13:932842. doi: 10.3389/fmicb.2022.932842.
(13)Ruofei Feng(通讯作者). Pseudorabies Virus ICP0 Abolishes Tumor NecrosisFactor Alpha-Induced NF-κB Activation by Degrading P65. Viruses. 2022;14(5):954. Doi:10.3390/v14050954.
(14)Ruofei Feng(通讯作者). DDX56 antagonizes IFN-β production to enhance EMCVreplication by inhibiting IRF3 nuclear translocation[J].Vet Microbiol. 2021 Dec13;264:109304. Doi: 10.1016/j.vetmic.2021.109304.
(15)Ruofei Feng(通讯作者). HSP27 ProteinDampens Encephalomyocarditis Virus Replication by Stabilizing MelanomaDifferentiation-Associated Gene 5. Front Microbiol. 2021 Nov 26;12:788870. Doi:10.3389/fmicb.2021.788870.
(16)Ruofei Feng(通讯作者). Pseudorabies Virus US3 Protein Inhibits IFN-β Productionby Interacting With IRF3 to Block Its Activation[J].Front Microbiol. 2021 Oct22;12:761282. Doi: 10.3389/fmicb.2021.761282.
(17)Ruofei Feng(通讯作者). Host protein, HSP90β, antagonizes IFN-β signalingpathway and facilitates the proliferation of encephalomyocarditis virus invitro[J].Virus Res. 2021 Nov;305:198547. Doi: 10.1016/j.virusres.2021.198547.
(18)Ruofei Feng(通讯作者).Encephalomyocarditis virus abrogates the IFN-βsignaling pathway via its structural protein VP2[J].Journal of Virology,2020.12. Doi: 10.1128/JVI.01590-20.
(19)Ruofei Feng(通讯作者). TransmembraneProtein 39A Promotes the Replication of Encephalomyocarditis Virus via AutophagyPathway[J]. Front. Microbiol., 2019;10:2680. Doi: 10.3389/fmicb.2019.02680.
(20)Ruofei Feng(通讯作者). Host antiviral protein IFITM2 restrictspseudorabies virus replication[J]. Virus Res., 2020; 287: 198105. Doi:10.1016/j.virusres.2020.198105.
(21)RuofeiFeng(通讯作者). Construction, expression,and characterization of a single-chain variable fragment (ScFv) antibodytargeting to the encephalomyocarditis virus. J Med Virol. 2018 Feb 24. Doi: 10.1002/jmv.25065.
(22)RuofeiFeng(通讯作者).Transcriptional profiling ofhost cell responses to encephalomyocarditis virus (EMCV). Virol J. 2017 Mar 4;14(1):45. Doi: 10.1186/s12985-017-0718-4.
(23)RuofeiFeng(第一作者). National serosurvey of encephalomyocarditisvirus in healthy people and pigs in China. Archives of Virology. 2015 Dec;160(12):2957-64.Doi: 10.1007/s00705-015-2591-z)
(24)RuofeiFeng(第一作者).Isolation, molecular andphylogenetic analysis of encephalomyocarditis virus strain GS01 in China. Infect Genet Evol. 30(2015):19-26.Doi:10.1016/j.meegid.2014.12.004
(25)RuofeiFeng(第一作者).Infection dynamics ofhepatitis E virus in naturally infected pigs in a Chinese farrow-to-finishfarm. Infect Genet Evol. 2011,11:1727-1731. Doi:10.1016/j.meegid.2011.07.009
联系方式
电话:0931-2928315, 13639311305
E-mail: fengruofei@xbmu.edu.cn