生物技术系

一、基本信息

姓名：高昊

学历：研究生

学位：博士

毕业院校：兰州大学

职称：讲师

二、研究专长

主要研究领域：发育神经生物学；分子病毒学

研究方向：脑血管与疾病；病毒侵染机制

三、教学情况

本科生教学：承担《动物学》《发育生物学》《微生物学与免疫学》，《未来生物技术》共四门生工/生技专业本科教学课程。

四、主要科研成果

（一）主持/参与项目

ALDH1A1在兔出血症病毒感染中的作用与分子机制研究（主持，国家民委专项）

（二）代表性论文

1.T. Ma, H. Gao, J. Wu, J. Zhao, B. Chang, Z. Zhang, S. Zhang, B. Zhang, and J. Fang, Diselenides as novel effective fluorescence quenchers to construct a two-photon fluorescent probe for thiols in a mouse stroke model. Chemical Communications 61 (2025) 1910-1913.

2.M.T. Hafeez, H. Gao, F. Ju, F. Qi, T. Li, and S. Zhang, Transcriptomic Analysis Divulges Differential Expressions of Microglial Genes After Microglial Repopulation in Mice. International Journal of Molecular Sciences 26 (2025) 1494.

3.X. Gao, H. Gao, S. Wang, F. Tang, Y. Zhao, and Y. Li, Cholecystitis and cholangiocarcinoma: a two-sample Mendelian randomization study. BMC gastroenterology 25 (2025) 619.

4.Y. Zhang, D. Li, H. Gao, H. Zhao, S. Zhang, and T. Li, Rapamycin Alleviates Neuronal Injury and Modulates Microglial Activation After Cerebral Ischemia. Mol Neurobiol (2024).

5.H. Gao, F. Ju, R. Ti, Y. Zhang, and S. Zhang, Differential Regulation of Microglial Activation in Response to Different Degree of Ischemia. Front Immunol 13 (2022) 792638

6.T. Li, J. Zhao, and H. Gao, Depletion of Arg1-Positive Microglia/Macrophages Exacerbates Cerebral Ischemic Damage by Facilitating the Inflammatory Response. Int J Mol Sci 23 (2022).

7.Y. Xu, H. Zhao, Z. Wang, H. Gao, J. Liu, K. Li, Z. Song, C. Yuan, X. Lan, C. Pan, and S. Zhang, Developmental exposure to environmental levels of cadmium induces neurotoxicity and activates microglia in zebrafish larvae: From the perspectives of neurobehavior and neuroimaging. Chemosphere 291 (2022) 132802.